Manufacturer: Dragon Pharma
Brand Name: Arimidex
Arimidex 1 mg (100 tabs)
Item price: $1.07
Arimidex tablets are intended for the treatment of breast cancer in women who are in the last phase of the menopause (postmenopause). The drug is used to treat advanced and early hormone-positive cancer, including after 2-3 years of tamoxifen therapy. The main active ingredient is Anastrozole. It inhibits the activity of aromatase, an enzyme under the influence of which androstenedione turns into estradiol.
In breast cancer, a decrease in the concentration of estradiol in the patient’s body has a therapeutic effect. Anastrozole has a highly selective orientation, i.e., acts exclusively on the substance to which it is an inhibitor. Therefore, treatment with Arimidex does not affect the production of cortisol and aldosterone, and replacement therapy for these substances is not needed. Androgenic, progesterone and estrogenic activity of the drug is also not inherent.
Arimidex tablets are not prescribed during premenopause, in childhood, as well as with:
hypersensitivity to Anastrozole, other components of the drug;
therapy with estrogens, tamoxifen;
severe renal, liver failure;
Compatibility with other drugs
The interaction of Arimidex and other drugs has not been studied enough. It is precisely known that drugs containing female sex hormones reduce the effectiveness of this antitumor agent, and therefore should not be prescribed with it. The simultaneous administration of Arimidex and Tamoxifen is also not recommended, since the latter is able to weaken the pharmacological effect of anastrozole.
Studies on drug interactions with antipyrine and cimetidine indicate that the combined use of Arimidex with other drugs is unlikely to lead to a clinically significant drug interaction mediated by cytochrome P450.
There is no clinically significant drug interaction when taking Arimidex simultaneously with other commonly prescribed drugs.
At the moment, there is no information on the use of Arimidex in combination with other antitumor drugs.
There are no exact data that would speak about the effect of alcohol on the effect of Arimidex. Given the ability of ethyl alcohol to reduce the effectiveness of a number of drugs, it is strongly recommended that you refuse to drink alcohol during the treatment period.
Arimidex is usually prescribed in a dose of 1 mg. Take the drug once a day, it is strongly recommended to do this at the same time. The tablet must be swallowed whole, without chewing, while drinking water. The recommended duration of taking Arimidex as an additional treatment is up to 5 years.
Mild or moderate degree of renal failure does not require a change in the dose of the drug as well as a mild degree of liver failure.